Ideally located within minutes of the world-renowned Mayo Clinic and Mayo Clinic Hospital Saint Mary's Campus, the Best Western Rochester Hotel Mayo Clinic Area/St. Mary's is a family friendly home base for leisure and business travelers alike. A premier choice among Rochester hotels, Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's offers 149 comfortable guest rooms and suites, and over 8500 square feet of banquet space. Families love our onsite water park, spacious suites, complimentary Wi-Fi, easy access to downtown businesses, and an array of family activities in Rochester. When staying at Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's take advantage of our proximity to area attractions including Apache Mall, Mayo Civic Center, Mayowood Mansion, Olmsted County Fairgrounds, Plummer House, and Graham Arena. For Added convenience, Rochester International Airport (RST) is just eight miles away. Our guests also enjoy the locally owned and independently operated, Wildwood Sports Bar and Grill that's connected to the hotel. We look forward to your stay!